Nelfinavir mesylate
CAS No. 159989-65-8
Nelfinavir mesylate ( AG-1343 mesylate )
Catalog No. M12296 CAS No. 159989-65-8
A potent and orally bioavailable HIV-1 protease inhibitor with Ki of 2 nM; exhibits an antiviral EC50 of 30 nM in HIV-1 strain RF-infected CEM-SS cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 43 | In Stock |
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10MG | 67 | In Stock |
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25MG | 141 | In Stock |
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50MG | 239 | In Stock |
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100MG | 357 | In Stock |
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200MG | Get Quote | In Stock |
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500MG | Get Quote | In Stock |
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1G | Get Quote | In Stock |
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Biological Information
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Product NameNelfinavir mesylate
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NoteResearch use only, not for human use.
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Brief DescriptionA potent and orally bioavailable HIV-1 protease inhibitor with Ki of 2 nM; exhibits an antiviral EC50 of 30 nM in HIV-1 strain RF-infected CEM-SS cells.
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DescriptionA potent and orally bioavailable HIV-1 protease inhibitor with Ki of 2 nM; exhibits an antiviral EC50 of 30 nM in HIV-1 strain RF-infected CEM-SS cells; also inhibits the proliferation of NSCLC cells, as well as every cell line in the NCI60 cell line panel with mean GI50 of 5.2 uM, induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo.HIV Infection Approved
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SynonymsAG-1343 mesylate
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PathwayMicrobiology/Virology
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TargetHIV
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RecptorHIVprotease
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Research AreaInfection
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IndicationHIV Infection
Chemical Information
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CAS Number159989-65-8
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Formula Weight663.89
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Molecular FormulaC33H49N3O7S2
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESCC1=C(C=CC=C1O)C(=O)N[C@@H](CSC2=CC=CC=C2)[C@@H](CN3C[C@H]4CCCC[C@H]4C[C@H]3C(=O)NC(C)(C)C)O.CS(=O)(=O)O
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Chemical Name3-Isoquinolinecarboxamide, N-(1,1-dimethylethyl)decahydro-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylthio)butyl]-, (3S,4aS,8aS)-, methanesulfonate (1:1)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zhang KE, et al. Antimicrob Agents Chemother. 2001 Apr;45(4):1086-93.
2. Shetty BV, et al. Antimicrob Agents Chemother. 1996 Jan;40(1):110-4.
3. Gills JJ, et al. Clin Cancer Res. 2007 Sep 1;13(17):5183-94.
2. Shetty BV, et al. Antimicrob Agents Chemother. 1996 Jan;40(1):110-4.
3. Gills JJ, et al. Clin Cancer Res. 2007 Sep 1;13(17):5183-94.
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